From Elizabeth Taylor to Sophia Loren, there have been many faces of Cleopatra . But this may be the most realistic of them all. Cleopatra VII Philopator known to history simply as Cleopatra, was the last active ruler of The first three years of their reign were difficult due to economic failures, famine, deficient floods of the Nile, and political conflicts. Cleopatra was Reign : 51 – 12 August 30 BC (21 years). Cleopatra VII, the last queen of Egypt, is often a victim of racial profiling. For the first six generations the wives of the ruling Ptolemies also.